Development, Adaptation and Validation of Persian Progressive Aphasia Language Scale (PALS-P): A test for clinical practice in Persian speakers with Primary Progressive Aphasia

Background: Primary progressive aphasia (PPA) is a neurological condition characterized by progressive dissolution of language capabilities. The Progressive Aphasia Language Scale (PALS) is an easy-to-apply bedside clinical scale that is capable of capturing and grading the key language features essential for the classification of PPA. The objective of the present study was to develop and validate the Persian version of the PALS (PALS-P) as a clinical language assessment test.Methods: In this cross-sectional study, PALS was translated and adapted into Persian according to the international guidelines. A total of 13 subjects (33subjects with PPA and .3 control subjects without dementia) were included to evaluate the intra-rater reliability and discriminant validity of PALS-P.Results: The intra-rater reliability of the PALS-P within a 34-day interval was strong for each sub-test (ICCagreement range = 3203-323). There were statistically significant differences between groups on PALS-P, suggesting its discriminative validity.Conclusion: This preliminary study revealed that the PALS-P was successfully developed and translated. The PALS-P may be a valid and reliable screening tool to assess language skills in Persian-speaking subjects with progressive aphasia

Keywords:

PPA , Aphasia , Progressive Aphasia Language Scale