Zink deficiency and Demographic characteristics effect in febrile seizure

Background: A febrile seizure occurs in 2-4% of children aged 6 months to 5 years. A simple febrile seizure is the most common seizure in children. According to the evidence both genetic and environmental factors affecting the occurrence of the disease. The purpose of this study was to determine the association between Zink deficiency and sociological factors with febrile seizures. Methods: This case-control study evaluated 136 children in the pediatric ward of the 22 Bahman hospital, Gonabad, Iran, from July 2015 to March 2017. 36 children aged 6 months to 5 years with febrile seizure selected as case group and 100 children Febrile without a seizure in the same age chosen as the control group. Demographic characteristics, presence or absence of preschool, place of residence, and family history of seizures and Zinc serum level recorded and Data were analyzed by frequency, mean, standard deviation, ANOVA, and chi-square statistical tests. Odds ratios were estimated by logistic regression at a confidence level of 95%.Results: 38.8% of the cases with FS and 5.0% of children with febrile without seizure had Zinc-deficiency. Serum Zink level in the case group was 75.44±16.98 and in the control group was 100.27±24.23. The Odds ratio for Zinc-deficiency in the patients with FS compared to the febrile children without convulsion was 1.069 (1.151_1.045). Conclusion: 38.8% of the cases with FS and 5.0% of children with febrile without seizure had Zinc-deficiency. Serum Zink level in the case group was 75.44±16.98 and in the control group was 100.27±24.23. The Odds ratio for Zinc-deficiency in the patients with FS compared to the febrile children without convulsion was 1.069 (1.151_1.045).

Keywords:

Zink deficiency , Demographic characteristics , febrile seizure