Hamidreza Hasani, - Eye Research Center, The Five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Marjan Razi-Khosroshahi, - Eye Research Center, The Five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran

Purpose: To investigate color changing effect of Nd: YAG laser on the surface of domestic sheep iris and to review the current literature on eye color changing methods.Methods: We extracted the iris of a domestic sheep and applied Nd: YAG laser on the surface. The Laser wavelength setting was 1064 nm, energy of 6 mj, spot size of 8 microns and 1 pulse for each burst. Then we reviewed the literature and added the available eye color changing methods. Results: The targeted spots were all depigmented without puncturing the iris. When a – 20 D was placed between the target and the laser source, the spots were bigger in size. Conclusion: 1064 nm Nd: YAG laser can effectively depigment the iris surface.