hydroxychloroquine retinal toxicity

Purpose: to present a case with rapidly progressive hydroxychloroquine retinopathy Methods: Retrospective evaluation of patient medical record. Results: A 37-year-old female presented with bilateral gradually decreasing visual acuity since 1 month ago. Diagnosed as rheumatoid arteritis, she was receiving hydroxychloroquine ( HCQ ) since 2 months ago. At presentation, the best corrected visual acuity was 8/10 in her right eye and 9/10 in her left eye.. Fundus examination revealed bilateral macular mottling changes, which showed delayed staining at fluorescein angiography. She was diagnosed as HCQ toxicity, advised to stop drug usage. Conclusion: while HCQ retinal is mostlty seen after longterm drug usage, reported cases of soon toxicity emphasizes the importance of baseline visit and meticulous follow up.