Investigating the Causes, Clinical Specifications and Prognosis of Wound Opening after Corneal Transplantation in Khatam Center of Ophthalmology

Purpose: The purpose of this study was to evaluate the predisposing factors, causes, clinical features, complications and prognosis of patients with wound dehiscence after corneal transplantation in Khatam Ophthalmology Hospital during 2007-2018. Methods: This study was performed on all records of patients with wound dehiscence diagnosis and history of corneal transplantation in Khatam Eye Hospital during the period of 2007-2018. Results: This study was performed on 45 patients (31 males / 14 females) aged between 8-79 years and mean age of 37.55 ± 20.04 years. In 35 cases (77.8%) the causative factor was trauma and followed by wound dehiscence after suture removal in 10 cases(22.2%).The time interval from corneal transplantation to wound dehiscence ranged from 1 day to 28 years, with a mean of 2.99±5.24 years and a median time of 270 (32,5- 1277,5) days. The final vision ranged from NLP to BCVAlog10 = -0.45. In the final exam, 66% of the subjects had the vision of CF and more and the best visual endpoint was VA 0.9 .The most commonly complications were IOP rise in 10 (23.3%), glaucoma in 5 (11.6%), graft rejection in 5(11, 6%), aphakia in 3(8, 3%), vitreous hemorrhage in2(5, 4%), iris prolapse in 1(4, 3%) of patients. Conclusion: All patients who have underwent a corneal transplant are at lifelong risk of wound dehiscence. In the vast majority of our cases wound dehiscence has occurred in the first 3 years after transplantation. Trauma is the leading cause of wound dehiscence especially work related traumas.