Synthesis of bis(isoindoline-1,3-dione)compounds

A simple synthesis of bis(isoindoline-1,3-dione)compounds from heterocyclic ketene aminals and diethyl-2-(3-oxo-2-isoindoline-1-ylidene)malonate is described. The present method offers desirable advantages including easy accessibility of reactants, mild conditions, absence of a catalyst, simple workup, and easy purification procedure. The products were confirmed by 1H and 13CNMR, IR, mass analyses

Keywords:

Heterocyclic compounds , Acetylancetone , 1 , n-diamines , Heterocyclic ketene aminals , Phthalic anhydride