Newly in diagnosis of type 1 diabetes mellitus

Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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GDRC12_001

تاریخ نمایه سازی: 5 بهمن 1398

Abstract:

Introduction: Newly in diagnosis of type 1 diabetes mellitus As defined by the ADA, the diagnosis of diabetes is made when: fasting plasma glucose is 126 mg/dl ≤, 2-hour plasma glucose in oral glucose tolerance test 200 mg/dl ≤ , random glucose is 200 mg/dl ≤ in presence of classic symptoms of hyperglycemia, or HbA1c is 6.5% ≤. In pediatrics, HbA1c remains controversial. Differential diagnoses of diabetes are diagnostic challenges. For example, in transient benign hyperglycemia due to stress, plasma glucose may occasionally reach levels of 250-350 mg/dl. In this condition, insulin or c-peptide level will be elevated, but in new onset of type 1 diabetes will be inappropriately normal or mildly low. Also, measurement of diabetes auto antibodies with or without assessment of beta cell integrity by measuring FPIR can be decisive.Materials & Methods: Newly in diagnosis of type 1 diabetes mellitus As defined by the ADA, the diagnosis of diabetes is made when: fasting plasma glucose is 126 mg/dl ≤, 2-hour plasma glucose in oral glucose tolerance test 200 mg/dl ≤ , random glucose is 200 mg/dl ≤ in presence of classic symptoms of hyperglycemia, or HbA1c is 6.5% ≤. In pediatrics, HbA1c remains controversial. Differential diagnoses of diabetes are diagnostic challenges. For example, in transient benign hyperglycemia due to stress, plasma glucose may occasionally reach levels of 250-350 mg/dl. In this condition, insulin or c-peptide level will be elevated, but in new onset of type 1 diabetes will be inappropriately normal or mildly low. Also, measurement of diabetes auto antibodies with or without assessment of beta cell integrity by measuring FPIR can be decisive.Results: Newly in diagnosis of type 1 diabetes mellitus As defined by the ADA, the diagnosis of diabetes is made when: fasting plasma glucose is 126 mg/dl ≤, 2-hour plasma glucose in oral glucose tolerance test 200 mg/dl ≤ , random glucose is 200 mg/dl ≤ in presence of classic symptoms of hyperglycemia, or HbA1c is 6.5% ≤. In pediatrics, HbA1c remains controversial. Differential diagnoses of diabetes are diagnostic challenges. For example, in transient benign hyperglycemia due to stress, plasma glucose may occasionally reach levels of 250-350 mg/dl. In this condition, insulin or c-peptide level will be elevated, but in new onset of type 1 diabetes will be inappropriately normal or mildly low. Also, measurement of diabetes auto antibodies with or without assessment of beta cell integrity by measuring FPIR can be decisive.Conclusion & discussion: Newly in diagnosis of type 1 diabetes mellitus As defined by the ADA, the diagnosis of diabetes is made when: fasting plasma glucose is 126 mg/dl ≤, 2-hour plasma glucose in oral glucose tolerance test 200 mg/dl ≤ , random glucose is 200 mg/dl ≤ in presence of classic symptoms of hyperglycemia, or HbA1c is 6.5% ≤. In pediatrics, HbA1c remains controversial. Differential diagnoses of diabetes are diagnostic challenges. For example, in transient benign hyperglycemia due to stress, plasma glucose may occasionally reach levels of 250-350 mg/dl. In this condition, insulin or c-peptide level will be elevated, but in new onset of type 1 diabetes will be inappropriately normal or mildly low. Also, measurement of diabetes auto antibodies with or without assessment of beta cell integrity by measuring FPIR can be decisive.

Authors

Hosein Shabani Mirzaee

Assistant Professor of Pediatric Endocrinology, Pediatric Endocrinology Department, Bahrami Children s Hospital, Tehran University of Medical Sciences, Tehran, Iran