Dyslipidemia and microbiota

Dyslipidemia refers to a disorder that is generally caused by disruptions in lipoprotein metabolism and ultimately will result in abnormal amounts of lipids in the blood. Elevated or decreased levels of these lipids, which are referred to as Hyperlipidemia and Hypolipidemia respectively, are believed to be related to many cardio-metabolic diseases such as diabetes and various cardiovascular conditions.In regard to the causes of dyslipidemia, it can be either caused by genetics or individuals lifestyles. population studies of genetic association identified more than one hundred genes that could directly affect lipid levels. Hence, it is estimated that at least 40% of cases are caused due to genetic factors.Materials & Methods: we have analyzed electronic databases such as Pubmed, google scholar, science direct. for this search the following descriptors were considered: dyslipidemia , microbiota , metabolic disorders , children metabolic disease , lipid metabolism dysfunction , Results: probiotic consumption could be a safe way to reduce or treat symptoms of metabolic disorders such as dyslipidemia . other microbiota-based therapies such as FMT or prebiotic consumtion have significant effectiveness in treatment of these disorders.Conclusion & discussion: In this presentation, we try to introduce novel microbiome-based approaches to help with the treatment of dyslipidemia which is an inherited metabolic disorder. Consuming probiotics, diet-based therapies and Fecal Microbiome Transfer (FMT) are some of the modern approaches in this way. Therefore, it could be better to pay more attention to them instead of immediately treating patients with conventional methods that could result in several side effects.

Keywords:

microbiota , dyslipidemia , probiotic , inherited diseases