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Paper
Title

Evaluation of quality of life in patients with Thalassemia : A Review study

Year: 1398
COI: NORTHDENT01_015
Language: EnglishView: 185
نسخه کامل این Paper ارائه نشده است و در دسترس نمی باشد

Authors

Zeynab Khalili - Student Research Committee, Behbahan University of Medical Sciences, Behbahan, Iran
Hamed Hajizad - Student Research Committee, Behbahan University of Medical Sciences, Behbahan, Iran
Shahab Jasemi - Student Research Committee, Behbahan University of Medical Sciences, Behbahan, Iran
Maryam arshadi - Student Research Committee, Behbahan University of Medical Sciences, Behbahan, Iran
alireza rafie - student Research Comminttee, shahidbeheshti tehran university of Medical Sciences, tehren , iran

Abstract:

Introduction: Thalassemia is a group of autosomal recessive hemoglobinopathies that are caused by inherited deficiency in the synthesis of globin chains, and they decrease hemoglobin and red blood cells. In its malignant type, β-thalassemia major is responsible for the development of various mutations in the beta-globin gene, leading to a decrease in the production of beta-globin chain or its lack of production, resulting in severe hemolytic anemia. Therefore, this study was conducted to investigate thalassemia and quality of life in these patients.The first days after birth are marked and dependent on blood transfusions at regular intervals. Therefore, this study was conducted to investigate thalassemia and quality of life in these patients.Methods: This study was conducted as a systematic review by searching the googlescholar search engine and at the sites sid pubmed, magiran, sciencedirect and elmnet with thalassemic keywords, quality of life, thalassemia major during 2000-2018. The related articles were reviewed by the researcher based on the inclusion criteria of the thalassemia variable and the criteria for the withdrawal of the lack of access to the full text of the articles, and 43 articles of Persian and English were used.Finding: Thalassemia is the most common type of hereditary anemia in Iran and the world. According to the World Health Organization, about 4% of the people are carriers of the thalassemia gene and more than 11,000 thalassemia cases have spread throughout the country in different provinces. 64% of thalassemic children have lower quality of life than healthy children, mainly due to severe pain and illness. Thalassemic patients with symptoms of chronic anemia, lack of proper growth, enlargement of the spleen and liver, bone disorders, especially visible changes in the skull and facial bones, with alterations in appearance. One of the ways to treat them is through repeated blood transfusions, which, although they increase their lifespan, the most common complication is an increase in iron load, causing iron deposition in vital organs such as the heart, endocrine, liver and lung. Iron deficiency drugs such as deferoxamine are used to prevent complications.Conclusion: Studies have shown that thalassemia has a lot of physical and psychological effects on the individual and the family, causing disappointment, reduced social function and quality of life in them. Therefore, screening thalassemia in marriage volunteers is a good opportunity to prevent and control the disease.

Keywords:

Paper COI Code

This Paper COI Code is NORTHDENT01_015. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/984343/

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If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Khalili, Zeynab and Hajizad, Hamed and Jasemi, Shahab and arshadi, Maryam and rafie, alireza,1398,Evaluation of quality of life in patients with Thalassemia : A Review study,the 1st student congress of dentistry in the north,Sari,https://civilica.com/doc/984343

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Type of center: علوم پزشکی
Paper count: 50
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