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DNA Damage Induced by Mobile Radiation Exposure in Pregnant Mice

تعداد صفحات: 1 | تعداد نمایش خلاصه: 96 | نظرات: 0
سال انتشار: 1398
کد COI Paper: TOXICOLOGY15_136
زبان Paper: Englishglish
نسخه کامل Paper در کنفرانس ارائه نشده است و در دسترس نیست.

مشخصات نویسندگان Paper DNA Damage Induced by Mobile Radiation Exposure in Pregnant Mice

Nargess Moghadasi - Department of Occupational Health Engineering, School of Public Health, Iran University of Medical Science, Tehran, Iran
Ali Safari Variani - Department of Occupational Health Engineering, School of Public Health, Qazvin University of Medical Science, Qazvin, Iran
Agha Fatemeh Hosseini - Department of Biostatistics, School of Public Health, Iran University of Medical Science, Tehran, Iran
Azadeh Ashtarinezhad - Air Pollution Research Center, Department of Occupational Health Engineering, School of Public Health, Iran University of Medical Science, Tehran, Iran

چکیده Paper:

Introduction: Daily application of various devices like microwave, mobile phone, medical devices and etc. would put people in the risk of electromagnetic radiation exposure. As a non-thermal effects of electromagnetic waves on human cells, exposure to mobile radiation cause in generation of reactive oxygen species, which is resulted in oxidative stress. The most used frequency in GSM, global system for mobile communication, in Asia, is 900 MHz. This study has investigated the effects of mobile phone (915 MHz) – induced electromagnetic radiation on DNA damage and TAC in blood of pregnant mice and the preventive role of vitamin C as an antioxidant.Materials and Methods: 21 pregnant mice were divided into 3 groups (control, exposure and exposure plus vitamin). The exposure groups were exposed to mobile phone radiation (915 MHz and 0.045 μw/cm2 power density, 8 h/d for 10 days) during pregnancy. The exposure plus vitamin group was received vitamin C (200 mg\Kg) by gavage. After 5 days, the mice were anesthetized and their blood samples were collected from the heart. 8-OHdG and TAC were measured by analytical commercial kits. All data were analyzed by ANOVA-Tukey test using SPSS (24.)Results: Significant increase in 8-OHdG levels were observed in exposure group (42.439± 1.3 ng/ml) compare to control (36.29±1.92 ng/ml) and exposure plus vitamin C groups (31.051±1.046 ng/ml). The TAC levels in exposure group (0.054±0.003mM) and exposure plus vitamin C group (0.068±0.001mM) had a significant decrease compare to the control group (0.082±0.004mM) (p = 0.001).Conclusion: Electromagnetic radiation caused DNA damage in blood of pregnant mice RFR caused oxidative stress in pregnant mice and increased DNA damage biomarker level and changes in TAC level. Consumption of vitamin C could prevent these changes in some extent. Studies on non-ionizing radiation during pregnancy will help define threshold limit for its exposure for pregnant women and protect them.

کلیدواژه ها:

DNA Damage, Mobile Radiation, Stress Oxidative, Pregnancy

کد Paper/لینک ثابت به این Paper

برای لینک دهی به این Paper می توانید از لینک زیر استفاده نمایید. این لینک همیشه ثابت است و به عنوان سند ثبت Paper در مرجع سیویلیکا مورد استفاده قرار میگیرد:

https://civilica.com/doc/985000/

کد COI Paper: TOXICOLOGY15_136

نحوه استناد به Paper:

در صورتی که می خواهید در اثر پژوهشی خود به این Paper ارجاع دهید، به سادگی می توانید از عبارت زیر در بخش منابع و مراجع استفاده نمایید:
undefined, undefined و undefined, undefined و undefined, undefined و undefined, undefined,1398,DNA Damage Induced by Mobile Radiation Exposure in Pregnant Mice,پانزدهمین همایش سراسری سم شناسی ایران,Tehran,,,https://civilica.com/doc/985000

در داخل متن نیز هر جا که به عبارت و یا دستاوردی از این Paper اشاره شود پس از ذکر مطلب، در داخل پارانتز، مشخصات زیر نوشته می شود.
برای بار اول: (1398, Moghadasi, Nargess؛ Ali Safari Variani و Agha Fatemeh Hosseini و Azadeh Ashtarinezhad)
برای بار دوم به بعد: (1398, Moghadasi؛ Safari Variani و Hosseini و Ashtarinezhad)
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