Publisher of Iranian Journals and Conference Proceedings

Please waite ..
CIVILICAWe Respect the Science
Publisher of Iranian Journals and Conference Proceedings
عنوان
Paper

Extraction of imidacloprid from human biological samples using the QuEChERS method and its determination by high performance liquid chromatography (HPLC)

تعداد صفحات: 1 | تعداد نمایش خلاصه: 53 | نظرات: 0
سال انتشار: 1398
کد COI Paper: TOXICOLOGY15_153
زبان Paper: Englishglish
متن کامل این Paper منتشر نشده است و فقط به صورت چکیده یا چکیده مبسوط در پایگاه موجود می باشد.
توضیح: معمولا کلیه مقالاتی که کمتر از ۵ صفحه باشند در پایگاه سیویلیکا اصل Paper (فول تکست) محسوب نمی شوند و فقط کاربران عضو بدون کسر اعتبار می توانند فایل آنها را دریافت نمایند.

مشخصات نویسندگان Paper Extraction of imidacloprid from human biological samples using the QuEChERS method and its determination by high performance liquid chromatography (HPLC)

Zohreh Karimi - Department of Toxicology, Faculty of pharmacy, Mazandaran University of medical Sciences, Sari, Iran
Mohammad Shokrzadeh - Department of Toxicology, Faculty of pharmacy, Mazandaran University of medical Sciences, Sari, Iran
Ali Abbasi - Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran- Department of Community Medicine, Sari Branch, Islamic Azad University, Sari, Iran
Vahid Sharifi - Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran

چکیده Paper:

Introduction: Suicide attempt using the pesticides is an important health problem in different countries. Imidacloprid is a systemic insecticide and belongs to a class of chemicals called the neonicotinoids . Due to the complexity of biological matrices and low concentrations of analytes in these environments use of newly emerged extraction techniques which use small amounts of organic solvents is inevitable.In this research QuEChERS method was applied to extract imidacloprid from blood and liver tissue of a deceased body admitted to the legal medicine of Mazandaran.Materials and methods: The QuEChERS is a simple and fast extraction method which uses the low volume of organic solvents. Experimental factors affecting the extraction recovery were investigated and the optimum extraction conditions were determined. The blood and liver samples were extracted in the optimum extraction conditions and analyzed by HPLC.Results: Optimum extraction conditions were 3 ml of acetonitrile, pH = 5, 0.1 mg of Nacl and 0.4 gMgSO4 as adsorbent. At the optimum conditions LOD and LOQ were 0.02 and 0.06 ppm respectively. The HPLC mobile phase was 30% of acetonitrile and 70% of phosphate buffer (pH=2.3) with flow rate of 1 mLmin-1. Standard addition method was used for determination and the concentrations of 12 and 1.8 ppm were obtained in blood and liver respectively.Conclusion: By analyzing and optimizing the QuEChERS method variables after analyzing the results, this method can be used as a simple and effective alternative to the liquid-liquid extraction method. The advantages of this method are simple, fast and very low organic solvent volume.

کلیدواژه ها:

Imidaclopride, Extraction, QuEChERS, Biological samples, HPLC

کد Paper/لینک ثابت به این Paper

برای لینک دهی به این Paper می توانید از لینک زیر استفاده نمایید. این لینک همیشه ثابت است و به عنوان سند ثبت Paper در مرجع سیویلیکا مورد استفاده قرار میگیرد:

https://civilica.com/doc/985017/

کد COI Paper: TOXICOLOGY15_153

نحوه استناد به Paper:

در صورتی که می خواهید در اثر پژوهشی خود به این Paper ارجاع دهید، به سادگی می توانید از عبارت زیر در بخش منابع و مراجع استفاده نمایید:
undefined, undefined و undefined, undefined و undefined, undefined و undefined, undefined,1398,Extraction of imidacloprid from human biological samples using the QuEChERS method and its determination by high performance liquid chromatography (HPLC),پانزدهمین همایش سراسری سم شناسی ایران,Tehran,,,https://civilica.com/doc/985017

در داخل متن نیز هر جا که به عبارت و یا دستاوردی از این Paper اشاره شود پس از ذکر مطلب، در داخل پارانتز، مشخصات زیر نوشته می شود.
برای بار اول: (1398, Karimi, Zohreh؛ Mohammad Shokrzadeh و Ali Abbasi و Vahid Sharifi)
برای بار دوم به بعد: (1398, Karimi؛ Shokrzadeh و Abbasi و Sharifi)
برای آشنایی کامل با نحوه مرجع نویسی لطفا بخش راهنمای سیویلیکا (مرجع دهی) را ملاحظه نمایید.

Research Info Management

Certificate | Report Paper

Export Citation info of this Paper to research management softwares

علم سنجی و رتبه بندی Paper

مشخصات مرکز تولید کننده این Paper به صورت زیر است:
نوع مرکز: medical university
تعداد مقالات: 1,686
در بخش علم سنجی پایگاه سیویلیکا می توانید رتبه بندی علمی مراکز دانشگاهی و پژوهشی کشور را بر اساس آمار مقالات نمایه شده مشاهده نمایید.

New RelatedPapers

Share this paper

WHAT IS COI?

COI is a national code dedicated to all Iranian Conference and Journal Papers. the COI of each paper can be verified online.

Support