Antifungal effects of Lactobacillus acidophilus and Lactobacillus plantarum against Candida albicans

Introduction and Objectives: Probiotics are live microorganisms that, while consumed in sufficient quantities, can increase the microbial balance in the host’s gut and be beneficial to human health. The major probiotics include Lactobacillus spp, Bacillus spp, Bifidobacterium spp, Escherichia coli, and Saccharomyces cerevisiae. The purpose of this study was to evaluate the antifungal properties of L. acidophilus and L. plantarum on C . albicans isolated from HIV/ AIDS patients. Materials and Methods: Antifungal properties of both cells and CSFs of L. acidophilus and L. plantarum against C. albicans investigated by Co-aggregation, agar overlay and interference and broth microdilution. Results: Our finding showed that both cells and CSFs of L. acidophilus and L. plantarum had antifungal effects against C .albicans. For C. albicans, the antifungal effects of L. acidophilus and L. plantarum was higher than FLC. Conclusion: The antifungal effects of L. acidophilus and L. plantarum was higher than FLC on C .albicans.

Keywords:

antifungal effects , probiotic , lactobacilli , L. acidophilus , L. plantarum , C .albicans , AIDS/ HIV patients.