Molecular Characterization of Epidemiology of MDR Mycobacterium tuberculosis isolated from tuberculosis patients resistant to Ofloxacin and Ciprofloxacin
عنوان مقاله: Molecular Characterization of Epidemiology of MDR Mycobacterium tuberculosis isolated from tuberculosis patients resistant to Ofloxacin and Ciprofloxacin
شناسه ملی مقاله: MEDISM20_373
منتشر شده در بیستمین کنگره بین المللی میکروب شناسی ایران در سال 1398
شناسه ملی مقاله: MEDISM20_373
منتشر شده در بیستمین کنگره بین المللی میکروب شناسی ایران در سال 1398
مشخصات نویسندگان مقاله:
Saeed Zaker - Biology and Microbiology Department, Islamic Azad University, Parand Branch, Tehran, Iran
خلاصه مقاله:
Saeed Zaker - Biology and Microbiology Department, Islamic Azad University, Parand Branch, Tehran, Iran
Introduction and Objectives: Multidrug-resistant tuberculosis (MDR-TB) is anescalating problem, particularly in the developing countries such as Iran. Continuous surveillance of drug resistance is required for effective management of TB patients. Materials and Methods: The susceptibility patterns of clinicalMycobacterium tuberculosis strains were retrospectively analyzed from April2012 to March2018. Identification and drug susceptibility testing (DST) were performed using conventional and molecular methods. Results: A total of 3012 clinical specimens were collected form TB suspected patients. Of them, 100 (3.3%) were culture positive and assigned as M. tuberculosis by phenotypic and molecular methods. According to DST, 62M. tuberculosisstrains were pan-susceptible and 38 were resistant to at least one anti-TB drug. Seventeenisolates were also assigned as MDR-TB. Conclusions:there wasa relatively high rate of MDR-TB in our study. Hence, improved diagnosis and treatment of MDR-TB should be highly prioritized.
کلمات کلیدی: Multidrug-Resistant Tuberculosis, MDR, Iran
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/987489/