THE COMPARISON BETWEEN INTRAVENOUS PARACETAMOL (APOTEL) AND KETOROLAC IN RELIEFING THE TENSION HEADACHE OF PATIENTS WHO ARE VISITING IN EMERGENCY DEPARTMENTS OF SHIRAZ NAMAZEE HOSPITAL SINCE 2017

Background and Aim : Headache is the most common neurological symptom and one of the mostcommon medical complaints of people admitted to the emergency department. Since emergencyheadache control is one of the necessary measures, the necessity of selecting an analgesic withfewer side effects is much needed. Therefore, this study was designed to evaluate the effect ofparacetamol and intravenous ketorolac in patients with tension headache.Methods : This study is a triple blind clinical trial in patients admitted to emergency departmentof Shiraz Namazi Hospital with tension headache diagnosis in 1396. Subjects were randomlyassigned into two groups of intervention with ketorolac and paracetamol based on inclusion andexclusion criteria. Paracetamol 1000 mg and ketorolac 30 mg were injected to subjects at baselineand the severity of pain was recorded according to NRS scale.Results : Overall, 70 patients in the study were divided into two groups: paracetamol (n = 36) andketorolac (n = 34), with a mean age of 36.25 9 9.51 years. The study population consisted of 27men and 43 women. Mean pain intensity in the paracetamol group before the intervention, 30 and60 minutes after the study was 8.77 1. 1.01, 5.27 1. 1.27 and 1.38 1. 1.29, respectively, and in theketorolac group, 9.02 0. 0.904, 5.26 1. 1.18 There was no significant difference between the twogroups at this time (P value> 0.05). Time study also showed that both paracetamol and ketorolachad significant effect in reducing pain severity (P value <0.001).Conclusion : Overall, the results of this study showed that both paracetamol and ketorolac hadsignificant effects on pain reduction at the end of the first 60 minutes after the study, but there wasno difference between the two groups in terms of their effectiveness in reducing pain intens it y.Have the same effects in reducing pain.

Keywords:

Paracetamol , Intravenous Ketorolac , Headache , Emergency