The Therapeutic Effect of Hyaluronic Acid in Tennis Elbow: A Systematic Review on Current Literature

Introduction: Tennis elbow (TE) is a common, painful disease that usually occurs in middle-aged patients and often prevents them from daily activities. Despite several studies regarding its treatment, there is no certain evidence-based treatment for TE, except short-term pain relief. Among treatment strategies, hyaluronic acid (HA) employed recently for TE treatment, and there is not any consensus regarding its efficacy. The aim of this was to evaluate the efficacy of HA in tennis elbow through a systematic review and meta-analysis. Methods: A systematic review and meta-analysis have been done in November 2018. PubMed, Scholar and Scopus have been searched with MeSh based keywords. The articles evaluated with two independent investigators and the qualities of articles have been evaluated with Jadad scale. Finally the eligible articles entered to the study and efficacy parameters extracted from previous articles. Results and discussion: Totally 49 articles included in this study, which screened in case of quality and finally articles remained in this study. Duplicated articles were removed by EndNote and 49 articles remained. In first step 41 articles excluded due to irrelevant title and eight articles remained finally. In second step, the abstract reviewed carefully and six articles remained. Finally after evaluating the full text four articles entered to final evaluation. Conclusion: Base on literatures that was reviewed, HA had a most effectiveness in pain. But single injection of HA couldn’t benefit for treatment of severe pain in TE for long-term. The results indicated that HA has an acceptable efficacy and has a minimal side effect. References: 1. Petrella RJ, Cogliano A, Decaria J, Mohamed N, Lee R. Management of Tennis Elbow with sodium hyaluronate periarticular injections. Sports Med Arthrosc Rehabil Ther Technol. 2010;2:4. 2. Kaux JF, Samson A, Crielaard JM. Hyaluronic acid and tendon lesions. Muscles Ligaments Tendons J. 2016;5(4):264–269

Keywords:

Hyaluronic acid , Lateral Epicondylitis , Lateral Humeral , Tennis Elbow ,