Use of Suprathel® for burns: a systematic review

Introduction: Accelerating the process of wound healing, reducing the risk of infection, and decreasing pain and discomfort of the burn area are very important goals of burn treatment. In order to achieve these goals, the use of biosynthetic wound dressings has dramatically increased in recent years. Suprathel® as a biosynthetic wound dressing is used not only to treat partial-thickness burns but also totreat split-thickness skin graft (STSG) donor sites, full-thickness wounds, large-scale abrasions, and scar revisions. Methods: This study systematically reviews empirical evidence on the application of Suprathel in burns. Related keywords such as Suprathel, Effectiveness, Safety, and Cost were searched in PubMed, Cochrane, Scopus, and Embase databases. Finally, 14 publications were identified based on the inclusionand exclusion criteria. Results and Discussion: The findings were reported according to different aspects of Suprathel use i.e. safety, effectiveness, and cost-effectiveness. Regarding the safety and effectiveness of Suprathel use, we found desirable results, particularly for partial thickness burns and split-thickness skin graft donor sites. However, with regard to the cost-effectiveness of Suprathel use the results were notconclusive. Conclusion: Despite the desirable features of Suprathel in terms of effectiveness, safety, and ease of use, the cost factor is one of the important limitations of the use of this material. However, due to the lack of comprehensive studies on the quantification of all factors, there is insufficient scientific evidence to make reliable conclusions from this systematic review.

Keywords:

Suprathel , Burn , Dressing , Effectiveness , Cost