y matsuo - Graduate School of Agriculture, Saga University, Saga, Japan
k nakai - Department of Development and Environmental Medicine, Graduate School of Medicine, Tohoku University, Sendai, Japan
I SAKUMA - Caress Sapporo Hokko Memorial Clinic, Sapporo, Japan . Health Science University of Hokkaido, Tobetsu, Japan
K AKUTSU - Food Chemistry Section ۱, Division of Hygienic Chemistry, Osaka Institute of Public Health, Osaka, Japan
N TATSUTA - Department of Development and Environmental Medicine, Graduate School of Medicine, Tohoku University, Sendai, Japan
M ISHIYAMA - Graduate School of Agriculture, Saga University, Saga, Japan

Background: Oily fish and their extracted oils may be a source of polychlorinated biphenyls (PCBs) which can induce toxic effects on the consumers. The main aim of this survey was estimation of PCBs intake through fish oil-derived dietary supplements and prescription drugs in the Japanese population.Methods: PCBs levels were determined in 20 fish oil-derived dietary supplements and 6 oil-derived prescription drugs from the Japanese market using Gas Chromatography-Mass Spectrometry. Then, the daily exposure to PCBs was estimated. Data were statistically analyzed using JMP software suite.Results: Totally, 17 of the 26 fish oil-derived products were contaminated with PCBs. The median PCB concentrations in the total set of fish oil-derived products was 2.2 ng/g oil wt. with a range of

Polychlorinated Biphenyls,Fish Oils,Dietary Supplements,Prescription Drugs,Risk Assessment,Japan,