The Use of Midazolam in Paediatric Dentistry: A Review of the Literature

Publish Year: 1393
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_RIJO-2-3_002

تاریخ نمایه سازی: 6 اسفند 1398

Abstract:

Context: Behaviour management and carrying out dental procedures for very young pre-cooperative, highly anxious or medicallydisabled children could be a challenging task. Various drugs and methods have been introduced to render treatment for this group ofchild patients. Midazolam is a benzodiazepine used as an adjunct to behaviour management techniques in the dental treatment of childpatients. Evidence Acquisition: To conduct this review of the literature, Pub-Med and Scopus were searched using the following terms: midazolam,oral, transmucosal, intravenous, intramuscular, rectal, premedication, paediatric dentistry, general anaesthesia. Fourty-five publishedpapers relating to the use of midazolam in paediatric dentistry were shortlisted out of an initial 124 publications and assessed accordingto the critical appraisal skills programme criteria. Randomized controlled trials, non- randomized studies, clinical trials and case reportswere reviewed with regard to midazolam s indications, contraindications, drug interactions and various administration routes whenused as a single sedative agents. Research and reviews based on the single-drug use of midazolam in children with adequate sample size aswell as clinical guidelines were included. However, those conducted on adult populations, using poly-pharmacy for sedation and clinicalinvestigations with flaws or non-significant results were excluded. Conclusions: Midazolam could be used as a safe and effective drug for conscious sedation, general anaesthetic premedication and thetreatment of seizures during dental treatment. However, further research on paediatric patients would be beneficial.

Authors

Mahshid Bagheri

Department of Pediatric Dentistry, Razavi Hospital, Mashhad, IR Iran