Publisher of Iranian Journals and Conference Proceedings

Please waite ..
Publisher of Iranian Journals and Conference Proceedings
Login |Register |Help |عضویت کتابخانه ها
Paper
Title

Comparison of Aprotinin and Controlled Hypotension on Blood Loss in the Herniated Intervertebral Disc Surgery

مجله بین المللی پزشکی رضوی، دوره: 3، شماره: 3
Year: 1394
COI: JR_RIJO-3-3_005
Language: EnglishView: 165
This Paper With 5 Page And PDF Format Ready To Download

Buy and Download

با استفاده از پرداخت اینترنتی بسیار سریع و ساده می توانید اصل این Paper را که دارای 5 صفحه است به صورت فایل PDF در اختیار داشته باشید.
آدرس ایمیل خود را در کادر زیر وارد نمایید:

Authors

Mehdi Fathi - Surgical Oncology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
Saeid Jahanbakhsh - Surgical Oncology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
Hosein Saadatfar - Faculty of Medicine, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, IR Iran
Alireza Bameshki - Surgical Oncology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
Marjan Joudi - Surgical Oncology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
Mehryar Taghvi Gilani - Surgical Oncology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran

Abstract:

Background: Methods of reducing blood loss in surgical procedures such as spinal disc herniation, which are characterized by severe bleeding, can reduce the need for blood transfusion and thereby the risk of infectious diseases transmission, transfusion reactions, acute lung injury, graft-versus-host disease (GVHD), hypothermia, coagulation disorders and metabolic complications. Anti-fibrinolytic drugs (e.g. Aprotinin, aminocaproic acid, desmopressin and tranexamic acid) and controlled hypotension (monitored reduction by medication) are among these methods.Objectives: In our clinical trial, two methods of aprotinin and controlled hypotension are compared in terms of their efficacy in reducing blood loss.Patients and Methods: 70 patients undergoing spinal disc herniation were randomly divided into two groups of controlled hypotension (treated with nitroglycerin: starting with 5 μg/minute to reach an MAP of 55 - 60 mmHg, with an increase of 5 μg/minute of the drug in every 3 - 5 minutes) and aprotinin (0.5 million units injection before surgery). The anesthesia was administered similarly to both groups and blood pressure and heart rate were recorded every 5 to 15 minutes. Moreover, the amount of bleeding and the surgeon satisfaction were measured.Results: 70 patients were identical in terms of demographics and the length of surgery. The two groups were not statistically different in terms of mean change in systolic, diastolic and mean blood pressure and heart rate at different times. The severity of blood loss measured on Boezarrt scale for low, medium and severe bleeding was respectively 21 (30%), 27 (39%), and 12 (31%). The extent of surgeon satisfaction with the operation room measured on a 3-point Likert scale (poor, medium and good) was 18 (26%), 40 (57%), and 12 (17%), respectively. The results were almost corresponding in both groups. Also, the two groups were identical in terms of calculated blood loss and the need for additional intraoperative medication.Conclusions: In intervertebral herniated disc surgery, aprotinin and controlled hypotension treatments yielded similar results in terms of reducing blood loss and surgeon satisfaction with the field of operation.

Keywords:

Paper COI Code

This Paper COI Code is JR_RIJO-3-3_005. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/994465/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Fathi, Mehdi and Jahanbakhsh, Saeid and Saadatfar, Hosein and Bameshki, Alireza and Joudi, Marjan and Taghvi Gilani, Mehryar,1394,Comparison of Aprotinin and Controlled Hypotension on Blood Loss in the Herniated Intervertebral Disc Surgery,https://civilica.com/doc/994465

Research Info Management

Certificate | Report | من نویسنده این مقاله هستم

اطلاعات استنادی این Paper را به نرم افزارهای مدیریت اطلاعات علمی و استنادی ارسال نمایید و در تحقیقات خود از آن استفاده نمایید.

Scientometrics

The specifications of the publisher center of this Paper are as follows:
Type of center: علوم پزشکی
Paper count: 8,097
In the scientometrics section of CIVILICA, you can see the scientific ranking of the Iranian academic and research centers based on the statistics of indexed articles.

New Papers

Share this page

More information about COI

COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

The COI is the national code of documents indexed in CIVILICA and is a unique and permanent code. it can always be cited and tracked and assumed as registration confirmation ID.

Support