Could Molecular Studies Save Hydroxyethyl Starch from Total Disappearance
Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_SBMU-3-4_004
تاریخ نمایه سازی: 6 اسفند 1398
Abstract:
Hydroxyethyl starch (HES) solutions have mainly been indicated as volume expanders . Recent unfavorable reports of these solutions such as probability of kidney injury or inducing coagulopathy have relatively ejected these solutions in many centers, particularly in European countries. Despite several confirming studies, multiple anecdotal letters or reviews has challenged total disappearance of these colloids from medicine practice. In addition, some novel observations emphasized to distinguished ability of HES to preserve the microvascular integrity even at the presence of an inflammatory process. Despite extreme statements has been published demanding immediate suspension of these fluids from the market, it seems logical to revise the most recent studies which may declare new pathways to approach HES family of solutions.
Keywords:
Authors
Parisa Sezari
Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Kamran Mottaghi
Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Masoud Nashibi
Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Farhad Safari
Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran