Valuation of anticoccidial activity of pulverulent extracted from Calotropis procera against coccidial infection in grasscutters

Coccidiosis is a disease that is highly feared by breeders because it involves a high mortality rate among young people, which can reach 80 to 100% of the population. This work aims essentially to valorize medicinal plants at lower cost in the farms and to contribute to the improvement of breeding practices of grasscutters in Benin. The present work has made it possible, using the extraction of the latex extract, to obtain from a volume of 42 cl of latex a total weight of 396 g of Calotropis procera extract with a yield of 31.42%. The coprological analyzes to constitute the batches of the infested animals made it possible to record a rate of animals infested with 80%. With varying infestations between 500 and 4000 eggs per gram of droppings. The experimental treatment concerned 100 grasscutters, which are divided to four equal groups. All 25 grasscutters of group 4 were not infested, Those in groups 1-3 were medicated with 0.5, 0.9 and 1.3 g extract/kg body weight. The oocyst counts and mortality rates were recorded to evaluate the anticoccidial efficacy. According to our results, the 0.5 g/kg dose administered to the subjects showed that on day 5 the infested individuals were not cured and 100% mortality was recorded in the 2000 groups ≥ EPG <4000 and EPG ≥ 4000. The 0.9 g/kg dose induced a decrease in the parasite load recorded on D5 in all the batches with a mortality rate of 44% for all 25 animals that received this dose and especially for the 2000 lot level ≥ EPG <4000 and EPG ≥ 4000. The best therapeutic effects were obtained with the administration of the dose d1,3 which induced a significant reduction (P<0,05) of oocysts in all subjects on day 4 with 4% of cases mortality (p<0.01).

Keywords:

Grasscutters , Coccidiosis , Calotropis procera , Pulverulent , Benin ,