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Cloning, expression, purification and antigenic evalution of vacA antigenic fragments recombinant protein of Helicobacter pylori

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Year: 2012
COI code: CIGS12_0050
Paper Language: English

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Authors Cloning, expression, purification and antigenic evalution of vacA antigenic fragments recombinant protein of Helicobacter pylori

  Leila Hasanzadeh - Department of Biotechnology and Microbiology, Arak University of Medical Sciences, Arak, Iran
  Hamid Abtahi - Molecular and Medicine Research Center, Department of Microbiology, Arak University of Medical Sciences, Arak, Iran
  Safieh Soufian - Department of Biology, Payame Noor University, Arak, Iran
  Ehsanollah Ghaznavi-Rad - Department of Microbiology and immunology, Arak University of Medical Sciences, Arak, Iran

Abstract:

Helicobacter pylori is one of the important pathogens that infected epithelial cells of stomach. The vacuolating cytotoxin (vacA) is major bacterial factor involved in gastric injury. The aim of this study was to construct a recombinant protein containing antigenic regions of vacA and determining its antigenicity as a vaccine candidate.

Keywords:

Helicobacter pylori, vacA cytotoxin, Cloning, antigeric regions

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COI code: CIGS12_0050

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Hasanzadeh, Leila; Hamid Abtahi; Safieh Soufian & Ehsanollah Ghaznavi-Rad, 2012, Cloning, expression, purification and antigenic evalution of vacA antigenic fragments recombinant protein of Helicobacter pylori, 12th Congress of Iranian Genetics Society, تهران, انجمن ژنتيك ايران, https://www.civilica.com/Paper-CIGS12-CIGS12_0050.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Hasanzadeh, Leila; Hamid Abtahi; Safieh Soufian & Ehsanollah Ghaznavi-Rad, 2012)
Second and more: (Hasanzadeh; Abtahi; Soufian & Ghaznavi-Rad, 2012)
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Type: Medical University
Paper No.: 411
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