Published in: 12th Congress of Iranian Genetics Society
COI code: CIGS13_0064
Paper Language: English
How to Download This Paper
For Downloading the Fulltext of CIVILICA papers please visit the orginal Persian Section of website.
Authors Evaluation of aqeouus and methanolic extract green tea and losing weight in obesity miceIman seyhoon - pharmaceutical sciences Branch, Islamic Azad University,Tehran , Iran
Azade Ebrahim-Habibi - Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran
Mahsa M. Amoli - Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran
Abstract:Green tea consumption has been recommended to have defensive activity against many chronic diseases, including Metabolic Syndrome such as type 2 diabetes It has been observed in mice that green tea reduce blood glucose levels and Indeed losing weight when included in the diet. Green tea polyphenols may influence regulation of blood glucose levels at a number of diverse points including at the level of carbohydrate digesting enzymes, specifically by inhibiting enzymes α- amylase and α-glucosidase . Two special types of α-amylase exist in the human body, salivary α-amylase and pancreatic α- amylase. Both types of α-amylase aid in the digestion of starch. Methods: NMRI female mice were randomly divided into two groups. Test group and control group took high fat diet food (including sesame seeds and creamy biscuits) during 8 weeks and only test group took aqueous and methanolic extract green tea during the same time. After 8 weeks, body weight and biochemical parameters of the two groups (alpha amylase) were measured. Liver hepatocytes were isolated using enzymatic degradation method. After RNA isolation and cDNA synthesis, real time PCR was done with specific primer for the Amy-1 gene and Then, the data were analyzed by SPSSsoftware. Results: We found that aqueous and methanolic extract green tea dose-dependently inhibited α-amylase in a cell-free system and hascrucial role in losing weight Correspondingly ,results showed significant association between aqueous and methanolic extract green tea and losing weight in obese mice. Conclusion: In the present study, we examined the acute effect of aqueous and methanolic extract green tea on the digestion and postprandial effects of oral carbohydrates in mice. We report that cotreatment with aqueous and methanolic extract green tea at a dose equivalent to 1 cups of green tea reduced the postprandial elevation in blood glucose levels and induced losing weight in obese mice .
Keywords:α-amylase ,aqueous and methanolic extract green tea, obese mice, losing weight
COI code: CIGS13_0064
how to cite to this paper:If you want to refer to this article in your research, you can easily use the following in the resources and references section:
seyhoon, Iman; Azade Ebrahim-Habibi & Mahsa M. Amoli, 2014, Evaluation of aqeouus and methanolic extract green tea and losing weight in obesity mice, 12th Congress of Iranian Genetics Society, تهران, انجمن ژنتيك ايران, https://www.civilica.com/Paper-CIGS13-CIGS13_0064.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (seyhoon, Iman; Azade Ebrahim-Habibi & Mahsa M. Amoli, 2014)
Second and more: (seyhoon; Ebrahim-Habibi & M. Amoli, 2014)
For a complete overview of how to citation please review the following CIVILICA Guide (Citation)
The University/Research Center Information:
Type: Azad University
Paper No.: 445
in University Ranking and Scientometrics the Iranian universities and research centers are evaluated based on scientific papers.
Research Info Management
Export Citation info of this paper to research management softwares
New Related Papers
- Study of genetic variation in chickpea (Cicer arietinum L.) genotypes based on ISSR markers and evaluation of resistance to Fusarium wilt
- Characterization of stem cells isolated from peritoneal dialysed fluid
- Association between genetic polymorphism of catalase (CAT) C-262T, Cu/Zn superoxide dismutase (SOD1) A251G and risk of Age-related macular degeneration (AMD)
- Regional variation in subclade of Leptosphaeria biglobosa
- Genetic study of external egg quality traits of native chicken of North of Iran
The Above articles are recently indexed in the related subjects
Iran Scientific Advertisment Netword
Share this paper
WHAT IS COI?
COI is a national code dedicated to all Iranian Conference and Journal Papers. the COI of each paper can be verified online.