Breast Cancer Risk Based on the Gail Model and its Predictors in Iranian Women

Backgrounds: This study was carried out to examine breast cancer risk and its fertility predictors in womenaged ≥35.Material and method: This cross-sectional study was conducted on 560 healthy women referred tohealth centers of Tabriz-Iran, 2013-2014. Five-year and lifetime risk of developing breast cancer were determinedusing the Gail model. General linear modeling was applied to determine breast cancer predictors .Result: Themean age of the subjects was 42.7 (SD: 7.7) years. Mean 5-year and lifetime risks of developing breast cancerwere determined to be 0.6% (SD: 0.2%) and 8.9% (SD: 2.5%), respectively. Variables of family history of breast cancer, age, age at menarche, parity, age at first childbirth, breastfeeding history, frequency of breastfeeding, method of contraception, marital status and education were all found to be predictors of breast cancer risk.Conclusion: According to the results of this study, screening programs based on the Gail model should beimplemented for Iranian people who have a high risk for breast cancer in order to facilitate early detection andbetter plan for possible malignancies