Flavonoid from Chaerophyllum macropodum

Flavonoids derivatives one of important secondary metabolism products, occur in the plants and classified in polyphenolic group. These compounds have some very important medicine and biological especially antiradical, antioxidant and prevent cancer effects [1]. The genus Chaerophyllum (Family: Umbelliferae) is represented in Iran by eight species, among which two are endemic: C. nivale Hedge et Lamond and C. khorassanicum Czern.ex Schischk. Chaerophyllum species are widely distributed in Europe, Iran, Caucasus and Central Asia, while C. macropodum is only known wild species in Iran and Turkey [2, 3]. In this study, the aerial part of Chaerophyllum macropodum was collected from Khalkhal area and dried in shade and then subjected to methanol extraction. A flavonoid has been isolated from the leaves of C. macropodum and purified by column chromatography, TLC and preparative TLC techniques. The structure was elucidated by using UV, H-NMR, C-NMR, HMBC, HMQC and IR spectra.