Omega-3 fatty acids intake in patients with uterus cancer referred to the clinic

Uterus cancer is a chronic disease in women that causing main problems such as infertility. Long-chain omega-3 fatty acids are types of polyunsaturated fatty acids (PUFAs) presented in fish. According toseveral studies, consumption of omega -3 fatty acids can slow down the growth of cancers, increase the effectiveness of chemotherapy and decrease the side-effects of chemotherapy. Omega-3 fatty acids contribute to some molecular mechanisms such as: 1) inhibiting the expression of cyclooxygenase in tumors, therefore, reducing progression of cancer cells and decreasing angiogenesis in tumor; 2)repressing nuclear factor-kB function and bcl-2 expression, therefore, allowing apoptosis of cancer cells. This cross-sectional study was done on 70 women with uterus cancer. They were randomlyselected from patients with uterus cancer that referred to clinic during 3 months.These patients filled the Food frequency questionnaire including the amounts of omega-3 (fish and supplements) consumption per year. Data analysis was done by SPSS software (version20). A p-value of ≤0.05 was considered to indicate statistical significance. The results of this study show that 68.57% of patients with uterus cancer consumed omega-3(fish and supplements) less than 2 times per year. Our results suggest that intake of omega-3(fish or supplements containing omega -3) at least once a week may have protective effects against the development of uterus cancer

Keywords:

Cancer Prevention , Cancer Risks , Lifestyle and Cancer , Nutrition and Cancer , Cancer Treatment and Management