COI code: RROYAN20_299
Paper Language: English
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Authors Seminiferous Tubules Histoarchitecture Changes in Nandrolone Decanoate-Treated Male RatsP Farzipoour - Department of Biology, Faculty of Sciences, Urmia University Urmia, Iran
V Nejati - Department of Biology, Faculty of Sciences, Urmia University Urmia, Iran
E Hosein Najd Gerami - Department of Biology, Faculty of Sciences, Urmia University Urmia, Iran
A Shalizar-Jalali - Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University Urmia, Iran
Abstract:Background: Nandrolone Decanoate as an anabolic steroid is used for physique- and muscle mass-enhancing purposes by athletes. The misuse of this drug has irreparable consequences such as male infertility.Materials and Methods: Eighteen rats were randomly catego-rized into 3 groups; group 1 was served as a control and groups 2 and 3 received 3 and 6 mg/kg of Nandrolone Decanoate weekly through intra-muscular injections, respectively. After 8 weeks, the testicles were harvested and the seminiferous tu-bules histoarchitecture was analyzed.Results: The seminiferous tubules epithelium thickness in the Nandrolone Decanoate -receiving groups showed a significant decrease compared to the control group, while seminiferous tu-bules luminal diameter in the Nandrolone Decanoate -treated rats exhibited a significant increase compared to the control group. Conclusion: High doses of Nandrolone Decanoate can have negative effects on male reproductive system.
Keywords:Nandrolone Decanoate, Reproductive System, Semi-niferous Tubulest, Rat
COI code: RROYAN20_299
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Farzipoour, P; V Nejati; E Hosein Najd Gerami & A Shalizar-Jalali, 2019, Seminiferous Tubules Histoarchitecture Changes in Nandrolone Decanoate-Treated Male Rats, 20th congress on reproductive biomedicine and 15th congress on stem cell biology & technology, تهران, پژوهشگاه رويان, https://www.civilica.com/Paper-RROYAN20-RROYAN20_299.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Farzipoour, P; V Nejati; E Hosein Najd Gerami & A Shalizar-Jalali, 2019)
Second and more: (Farzipoour; Nejati; Hosein Najd Gerami & Shalizar-Jalali, 2019)
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The University/Research Center Information:
Type: state university
Paper No.: 11535
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