Effect of Structure and Composition of Functional Sutures on Wound Healing-a Review
Publish place: Third International Congress and Fifth National Congress on Wound and Tissue Restoration
Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
WTRMED05_024
تاریخ نمایه سازی: 5 آذر 1397
Abstract:
Background: Polymer sutures are natural or synthetic textile materials in monofilament, multifilament, twisted, and braided form, which are widely used in wound closure. Sutures are classified based on origin, absorbability, and structures. The using of antibiotics or other therapeutic agents in the suture structure has become an attractive and interesting research in wound healing. Objectives: This review attempt to describe key properties of sutures include physical, mechanical, handling, and biological properties. Also the types of functional sutures will present.Methods: Suture properties and fabrication techniques have been studied in this work. Among the different fabrication methods, electrospinning and melt spinning are used to produce functional sutures emphasizing their potential as drug delivery devices that are discussed in this study. Results and Discussion: The method of using nanoparticles, antibiotics, and other bioactive molecules in suture structure are studied. The role of medicated sutures for controlling the drug release will be discussed. In addition, advantages and drawbacks of each created structures are introduced. Conclusion and Future Perspectives: The role of polymers in the fabrication of reliable drug deliver sutures with functional properties is most important. We still have a long way to produce biocompatible and functional sutures with the desirable mechanical properties for wound healing goals.
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Authors
Maliheh Yaghoobi
PHD, Assistant Professor of Biomedical Engineering, Engineering Department, Faculty of Chemical Engineering, University of Zanjan, Zanjan, Iran