Synthesis of 2-aryl-1H-benzo[d]imidazole derivatives using nano montmorillonite clay as an efficient catalyst

Benzimidazoles are among the most important nitrogen-containing heterocyclic compounds that have many pharmaceutical applications; including, antitumor, anticancer, anticorrosive, antibacterial, irritant and enzymatic interceptors. In this research, the synthesis of benzimidazoles using o-phenylenediamine and aldehyde derivatives in the presence of the nano montemurillonite in solvent-free and room temperature conditions has been investigated. All products with relatively good yields were identified by spectral and physical methods.

Keywords:

Nano montemurillonite clay , Benzimidazoles , solvent-free conditions , heterocyclic compounds