Application of Novel Gel-CdTe/ZnS QDs nanosensor in drug determination

Nanosensors are mostly a chemical or mechanical sensors with variety of applications such as drug determination. Evaluation of tramadol, kanamycin, bromhexine, rifampicin, amantadine, and tetracycline drugs done by different kind of sensors. However, there is still a need for sensors with the high accuracy and sensitivity for low concentrationsof many drugs. In this study, we tried to develop a nanosensor for more drug determination by introducing a novel Gel-CdTe/ZnS QDs hybrid. Besides that, interaction of this nanosensor with Epirubicin (Ep) examined. In the presence of 36.45 × 10−6 mol/L Ep, 8.75% % of fluorescence intensity of Gel-CdTe/ZnS QDs was quenched at 575nm. This obviously illustrated that CMC -CdTe/ZnS QDs could have an interaction with Ep and decrease fluorescence intensity of this nanosensor

Keywords:

Nanosensores , Quantum Dots , Gelatin , Drug determination