Investigation of Catalytic Activity and Kinetics of a Pd/Biphenyl-based Phosphine System in the Ullmann Cross-coupling of Para-substituted Aryl Bromides
Publish place: Inorganic Chemistry Research، Vol: 4، Issue: 2
Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_ICR-4-2_004
تاریخ نمایه سازی: 22 دی 1399
Abstract:
Catalytic activity of a Pd/biphenyl based- phosphine system in the Ullmann cross-coupling reaction of various para-substituted aryl bromides were investigated. The results showed that the bulky electron-rich phosphine efficiently modify the electronic and steric properties of palladium center and promote the cross-coupling reaction. Mechanistic study using the Hammett correlation revels that electron-withdrawing substituents decrease the electron density at the palladium center and decrease the rate of oxidative-addition step such that this step will become the rate determining step (rds). On the other hand, electron-donating groups increase the rate of oxidative-addition step such that the reductive-elimination step will become the rds.
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Authors
Sara Eavani
Faculty of Chemistry, Razi University, Kermanshah, Iran
Ehsan Azadi
Faculty of Chemistry, Razi University, Kermanshah, Iran
Mohammad Joshaghani
Faculty of Chemistry, Razi University, Kermanshah, Iran