Microextraction and Determination Trace Amount of Propranolol in Aqueous and Pharmaceutical Samples with Oxidized Multiwalled Carbon Nanotubes

Due to the increasing use of drugs and growing environmental pollution, controlling the use of drugs and the ability to measure their small amount is an issue of great significance. The present study examined the determination of low amounts of propanolol based on solid phase microextraction method via spectrophotometry. In this work, the adsorbent was made on the basis of multi-walled carbon nanotubes supported by magnetic nanoparticles (MWCNT), followed by optimization. Various factors such as pH, organic solvent adsorption volume, extraction and desorption time, stirring rate and solvent type were examined for the purpose of optimization. For this objective, a spectrophotometer was used to obtain the maximum wavelength of propanolol (۲۱۴ nm) and to obtain the optimal conditions. The dynamic range was ۰.۰۲-۰.۳۵ mg/l. In addition, pre-concentration values, LOD and% RSD were ۲۶۸.۲۸, ۰.۰۲۲ mg/L and ۱.۷۶, respectively.

Keywords:

Removal , Propanolol , Multi-walled carbon nanotube , micro solid phase extraction , Magnetic nanoparticle