The Review of SARS-CoV-۲: Recent Perspective and Advances in Detection
Publish place: Infection Epidemiology and Microbiology، Vol: 6، Issue: 3
Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IEM-6-3_008
تاریخ نمایه سازی: 28 تیر 1400
Abstract:
Background: The outbreak of novel coronavirus (۲۰۱۹-nCoV), which began in Wuhan, China, has rapidly spread in many countries and is currently considered a pandemic. The virus (SARS-CoV-۲) causes severe acute respiratory syndrome and is related to SARS-CoV and MERS-CoV.
Methods: In this review, an introduction to SARS-CoV-۲ was provided comprising the following items: general features; pathogenesis; the existing knowledge on immunological properties; transmission routs; diagnostic features, especially discussion about new approaches for treatment and prevention; and different diagnostic methods including nucleic acid based assays, serological testing, and MALDI TOF-MS and LC-MS technologies.
Findings and Conclusion: Introducing the different methods for SARS-CoV-۲ detection may be useful to provide new insights into the development and improvement of detection primers, probes, methods/techniques, potential targets for drug designation, and therapeutic candidates against the virus.
Keywords:
۲۰۱۹-nCoV , Acute Respiratory syndrome , Nucleic acid base assays , Serological testing , MALDI TOF-MS and LC-MS
Authors
Hajar Mohammadi Barzelighi
Biosun Pharmed Factory, Barkat Pharmaceutical group, Tehran, Iran
Bahram Daraei
Department of Toxicology and Pharmacology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
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