Relationship between bone formation marker (BGLA- protein) with Adipokines and insulin resistance in overweight men after aerobic exercise

Objective: Osteocalcin a small peptide secreted by osteoblasts, has been recently described as a hormone involved in the regulation of energy metabolism. Also, experimental data suggest regulation of adipocytes by bone. The present study aims to Relationship between bone formation marker (BGLA- protein) with Adipokines and insulin resistance in overweight men after aerobic exercise. Method: Twenty two male volunteers with a mean age۳۱.۵۰±۲.۲۳years, body mass index(BMI) ۲۸.۶۷±۰.۹۶ kg.m۲, were randomly selected to control(n=۱۱) and aerobic training(n=۱۱) groups. Subjects in the aerobic training group participated in the ۸-week exercise training program, three sessions per week (۶۰ minutes at ۷۰ to ۸۵ percent of heart rate reserve(HRR). Weight, body fat % and BMI were analyzed, fasting blood samples were collected before and after the ۸-week exercise program to determine the serum Osteocalcin, leptin, adiponectin, insulin and HOMA-IR. Result: T-test showed that Body fat, BMI, weight, insulin, glucose, HOMA-IR and leptin were significantly reduced following the aerobic exercise(P

Keywords:

Osteocalcin , Adipokines , Insulin , Aerobic Training , Overweight