Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review
Publish place: Iranian Journal of Basic Medical Sciences، Vol: 25، Issue: 3
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJBMS-25-3_001
تاریخ نمایه سازی: 15 فروردین 1401
Abstract:
Objective(s): Ficus carica (fig) and Olea europaea (olive) are valuable nutritional plants that are widely used in diet and traditional medicine. Different parts of the plants such as fruit and leaves contain beneficial compounds with diverse pharmacological properties, among which anti-inflammatory activities are remarkable. The purpose of this review is to discuss the anti-inflammatory effects of F. carica and O. europaea with emphasis on their impact on pivotal pro-inflammatory cytokines including IL-۱, IL-۶, and TNF-α. Materials and Methods: To prepare the present review, the sites utilized included Scopus, PubMed, Science Direct, and Google Scholar and studied relevant articles from ۲۰۰۰ until ۲۰۲۱. Results: As a result, we observed that most of the compounds in fig and olive including polyphenols, flavonoids, etc., exert their anti-inflammatory effects through inhibiting or decreasing pro-inflammatory cytokines. Moreover, some natural antioxidants are common between these two plants. Conclusion: We suggest that consuming figs and olives simultaneously or alone can be useful in the prevention or treatment of inflammatory diseases.
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Authors
Lotfollah Rezagholizadeh
Department of Biochemistry, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
Maryam Aghamohammadian
School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
Mahya Oloumi
School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
Shokofeh Banaei
Department of Physiology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
Mohammad Mazani
Department of Biochemistry, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
Masoud Ojarudi
Department of Biochemistry, Faculty of Sciences, Payame Noor University, Tehran, Iran
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