The association between anthropometric parameters and cardiovascular risk indicators in women with polycystic ovarian syndrome
Publish place: ARYA Atherosclerosis، Vol: 16، Issue: 1
Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
View: 123
This Paper With 5 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_RYA-16-1_006
تاریخ نمایه سازی: 2 شهریور 1401
Abstract:
BACKGROUND: In patients with polycystic ovarian syndrome (PCOS), this is now hypothesized that whether increased risk for cardiovascular disorders is related more to obesity than PCOS per se. This study aimed to compare cardiovascular risk factors between the lean and obese women with PCOS.METHODS: This case-control study was conducted on ۸۶ (۴۳ obese and ۴۳ lean) women with PCOS. The presence of overweight and obesity was defined based on the body mass index (BMI) (> ۲۵ kg/m۲). The study objectives were first to compare mean levels of cardiovascular laboratory parameters between lean and obese patients with PCOS and then to assess the relationship between obesity indices and these laboratory parameters.RESULTS: Compared to the lean group, the obese group had significantly higher mean fasting blood sugar (FBS) (۸۹.۴۰ ± ۱۰.۷۳ versus ۸۴.۰۹ ± ۷.۸۷ mg/dl, P = ۰.۰۱۱), higher mean serum triglyceride (TG) (۱۱۹.۰۹ ± ۶۰.۶۶ versus ۹۶.۸۶ ± ۲۷.۲۳ mg/dl, P = ۰.۰۳۲), higher mean total cholesterol (۱۴۷.۷۰ ± ۵۷.۳۸ versus ۱۲۶.۷۹ ± ۳۵.۹۵ mg/dl, P = ۰.۰۴۵), and also higher mean low-density lipoprotein (LDL) (۹۲.۳۰ ± ۱۳.۵۳ versus ۸۳.۷۷ ± ۱۷.۶۱ mg/dl, P = ۰.۰۱۴). Using the Pearson’s correlation test, positive correlations were found between BMI and waist circumference (WC) indices and study parameters including FBS, serum TG, serum total cholesterol, serum LDL, and also blood pressure (BP).CONCLUSION: Because of higher concentrations of FBS and lipid profiles in obese patients with PCOS and considering obesity as a more important risk factor for coronary artery disease (CAD) than PCOS, it is recommended to assess and monitor cardiovascular risk factors in these population to reduce the risk for cardiovascular disorders and metabolic syndrome. Also, by reducing body weight and normalizing BMI value, the cardiovascular and metabolic risk factors can be modified and prevented.
Keywords:
Authors
Ahmad Mirdamadi
Associate Professor, Department of Cardiology, Najafabad Branch, Islamic Azad University, Najafabad, Isfahan, Iran
Soheila Riahinejad
Assistant Professor, Department of Gynecology, Najafabad Branch, Islamic Azad University, Najafabad, Isfahan, Iran
Samane Varnaseri
General Practitioner, Najafabad Branch, Islamic Azad University, Najafabad, Isfahan, Iran
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :