Risk of sudden cardiac death

Publish Year: 1392
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_RYA-9-5_002

تاریخ نمایه سازی: 3 شهریور 1401

Abstract:

BACKGROUND: The aim of this study was to determine characteristics of patients with sudden cardiac arrest (SCA) and/or sudden cardiac death (SCD). We need an effective risk stratification method for SCD in patients without low left ventricular ejection fraction (LVEF). METHODS: The study population of this cross-sectional study consisted of ۲۴۱ patients with SCA or SCD who were admitted to an academic hospital, in Tehran, Iran, from ۲۰۱۱ through ۲۰۱۲. SCD was defined as unexpected death from cardiac causes, heralded by abrupt loss of consciousness within one hour of the onset of acute changes in cardiovascular status, or an unobserved death in which the patient was seen and known to be doing well within the previous ۲۴ hours. Survivors of aborted SCD were also included in the study. Clinical and paraclinical characteristics as well as emergency department complications of patients were recorded. RESULTS: The mean age of population was ۶۶.۰ ± ۱۶.۵ (۱۷ to ۹۰ years). Among the patients, ۱۶۶ (۶۸.۹ %) were male, ۵۰ (۲۰.۷%) were smoker, ۷۷ (۳۲.۰%) had hypertension, ۴۷ (۱۹.۵%) had diabetes mellitus, ۲۱ (۸.۷%) had hyperlipidemia, and ۳۲ (۱۳.۳%) had renal insufficiency. According to New York Health Association (NYHA) functional class, ۳۱ (۱۲.۹%) patients were asymptomatic, ۴۲ (۱۷.۴) and ۹۹ (۴۱.۱%) subjects were in NYHA I and II, respectively and only ۶۹ (۲۸.۶%) patients were in NYHA III or IV. In this study, presenting arrhythmia was pulseless electrical activity or asystole which was observed in ۱۳۰ (۵۳.۹%) subjects. Ventricular tachycardia (VT) or ventricular fibrillation (VF) was seen in ۵۳ (۲۲%) patients. Cardiopulmonary resuscitation in emergency room was successful only in ۴۶ (۱۹.۱%) subjects. CONCLUSION: Low ejection fraction (EF) may be an independent predictor of sudden cardiac death in patients, but it is not enough. While implantable cardioverter defibrillators can save lives, we are lacking effective risk stratification and prevention methods for the majority of patients without low EF who will experience SCD.   Keywords: Death, Sudden Cardiac Arrest, Sudden Cardiac Death 

Authors

Roxana Sadeghi

Assistant Professor, Cardiovascular Research Center AND Department of Cardiovascular Disease, Loghman Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Nadia Adnani

Resident, School of Medicine, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Mohammad-Reza Sohrabi

Associate Professor, Department of Community Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Saeed Alipour Parsa

Assistant Professor, Cardiovascular Research Center AND Department of Cardiovascular Disease, Loghman Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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