Preparation and Characterization and Thermal Study of New Copolymers of Semicarbazide and Fatty Acids Derivatives with Malic Anhydride and Assess their Biological Activity

In this study, new semicarbazide derivatives [E۱-E۵] were prepared by the reaction of semicarbazide with different fatty acids (olic, linolic, linolinic, recenolic and cinnamic  acid) in DMF, then this compounds will polymerization with malic anhydride in H۲O۲ as initiator to get [EP۱-EP۵] .The prepared compounds were characterized by physical properties, UV-Vis, FT-IR, ۱H-NMR, ۱۳C-NMR and TGA analysis.TLC checked the purity for these compounds.The antibacterial activity were studied against different kinds  of bacteria, namlyStophylococcuceaures,Stophylococcuce Saprophytic and Protes.

Keywords:

Semicarbazide , fatty acids , Malic anhydride copolymers , Thermal study of fatty acid polymer , assential fatty acid semicarbazide