Aducanumab: A Novel Drug for Alzheimer's Disease; Future Challenges in Treatment

Dear Editor,Alzheimer's disease (AD) is a common frustrating disease among older adults. It imposes a high economic and medical burden on society and families. Although Alzheimer's disease is a progressively disabling psychiatric-neurological disorder, and there is no effective drug stopping or delaying the disease process over the last decade, lots of research has been done on some antibodies against amyloid plaques, which are the main etiology of this disease (۱). By June ۲۰۲۱, Aducanumab (Aduhelm®) was approved by the Food and Drug Administration (FDA); it was demonstrated that this drug could be an effective intervention to prevent and remove the formation of amyloid plaques (۲). Because of the lack of extensive research on this drug, many physicians and patients are concerned about its efficacy and side effects. However, many Alzheimer's specialists are satisfied with the approval of this drug.

Keywords:

Alzheimer’s Disease , Aducanumab , Amyloid-β