Evaluation of Outcome in Sticking Upper Limit and Lower Limit in BIS Monitoring for Radical Cystectomy

Background: The electroencephalogram-derived bispectral index (BIS) is a promising new method to assess anesthetic adequacy. The purpose of this study was to evaluation of outcome in sticking upper limit and lower limit in BIS monitoring for radical cystectomy surgery.Methods and Materials: A total of ۲۰۲ patients with elective radical cystectomy were selected randomly and divided into two groups of BIS (۴۰-۵۰) and BIS (۵۰-۶۰). The patients were blinded to the study group (BIS). Initially demographic and clinical information such as age, sex, weight, recovery time, patient extubation time, awareness during surgery, mortality rate and patient stay in hospital, BIS and patient cost were included in data collection form.Results: There were ۱۹۷ males and ۵ females and the average age of the patients were ۶۷.۱۲±۸.۱. There was significant relationship between recovery time, amount of anesthetic used, ICU stay, hospital stay, hospital cost, and BIS monitoring range (p<۰.۰۰۱). In addition, there was significant relationship between extubation time and BIS monitoring range (p=۰.۰۰۱). The relationship between PONV with BIS monitoring range is significant (p<۰.۰۰۱). But there was no significant relationship between analgesic drugs (p=۰.۲۶) and awareness (p=۰.۱۷۵) and mortality (p=۰.۶۵۱) with BIS monitoring range.Conclusion: By increasing the BIS value, the anesthetic dose, extubation and recovery time, hospital and ICU stay were significantly reduced as well as the cost.

Keywords:

Bispectral Index , Radical Cystectomy , Anesthesia