Aptamer base nanobiosensor for stress hormone measurement

Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
View: 108

This Paper With 7 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_JNCOG-0-4_004

تاریخ نمایه سازی: 11 دی 1401

Abstract:

Cortisol plays an important part in the physiological procedures. Observing cortisol concentration as a stress indicator demonstrates physiological mode for diagnosis goal. The mechanism of presented nanobiosensor is LSPR and performed based on the nucleic acid aptamer functionalized with gold nanoparticles which has specific interaction with cortisol. The interaction of aptamer particular measurement of cortisol was accomplished over the concentration from ۰.۰۵ -۰.۲ µg·mL-۱ within ۲۰ minutes. The detection limit is estimated to be ۰.۰۲ µg.mL-۱.

Authors

Fatemeh Mortazavi Moghadam

Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran; Division of Engineering in Medicine, Department of Medicine, Harvard Medical School, Brigham and Women’s Hospital, Cambridge, MA, ۰۲۱۳۹, USA

Mohammadreza Bigdeli

Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran

Su Ryon Shin

Division of Engineering in Medicine, Department of Medicine, Harvard Medical School, Brigham and Women’s Hospital, Cambridge, MA, ۰۲۱۳۹, USA