Synthesis, Spectral, Cancer Inhibitory Activity and Antimicrobial Studies of Cobalt(II) and Nickel(II) Metal Complexes Containing Azo Derived from ۲-Amino Benzimidazole
Publish place: Journal of Medicinal and Chemical Sciences، Vol: 6، Issue: 8
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JMCH-6-8_017
تاریخ نمایه سازی: 10 اسفند 1401
Abstract:
The production of the tridentate Azo ligand ۲-[۲/-(benzimidazolyl)azo]-۴-bromo-۶-chloro phenol (BIABrClP) complexes using Co(III) and Ni(II) is discussed in this article. Spectral methods including ۱H-NMR, UV-Vis, FT-IR, magnetic moment measurements, molar conductance, and elemental analysis were used to thoroughly explore the coordination mode of azo ligand containing NNO donor atoms with metal ions. The octahedral geometry for the synthesized Ni(II) and Co(III) complexes was suggested from the analytical and spectral studies. According to in vitro assays for antibacterial activity, the majority of produced compounds exhibit good action against a variety of microorganisms, including Candida albicans, Staphylococcus aureus, and Escherichia coli.
Keywords:
Synthesis Imidazolylazo dye Spectrum studies Breast cancer (MCF , ۷)
Authors
Neda Hasan
Dentistry Department, Al-Mustaqbal University College, Babylon, Iraq
Muhammed Abdel Hasan Shallal
Lecturer, M.Sc, Chemistry Field, Educational Directorate Thi-Qar, Thi-Qar, Iraq
Hayfaa A. Mubarak
Department Chemical Engineering, College of Engineering, University of Babylon, Iraq
Mustafa M.Karhib
Department of Medical Laboratory Techniques, Al-Mustaqbal University College, ۵۱۰۰۱ Hillah, Babylon, Iraq
Ahmed S Naje
Collage of Water Resource Engineering, AL-Qasim Green University, Babylon ۵۱۰۳۱, Iraq
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