Treatment of Rheumatoid Arthritis Based on Personalized Medicine: a New Approach in Rheumatology
Publish place: Personalized Medicine Journal، Vol: 8، Issue: 28
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_PMJ-8-28_006
تاریخ نمایه سازی: 16 اسفند 1401
Abstract:
In the twenty-first century, there still needs more clarity on rheumatoid arthritis (RA). Rheumatoid arthritis is a widespread but heterogeneous illness with a broad range in its history, clinical symptoms, and response to therapy. It is now known that prevention of joint destruction, functional impairment, and a poor disease prognosis depends on early, correct diagnosis and starting therapy with disease-modifying drugs (DMARDs), among which methotrexate (MTX) remains the gold standard in the treatment of RA. Early rheumatoid arthritis diagnosis is crucial since it enables a speedier start to primary therapy. Pharmacogenetic and pharmacogenomic research, which aid in identifying a patient’s genetic profile, may bring personalized treatment closer to reality. Identifying disease-specific genes while the organism’s resistance to them is still intact should be made feasible by further study into RA.
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Authors
Hossein Amin-Anaraki
Biotechnology Research Center, Islamic Azad University, East-Tehran Branch, Tehran, Iran
Saber Kabiri-Samani
Young Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.