Familial Mediterranean Fever (FMF): Mysterious Presentations and Challenging Points From Diagnosis to Management in Acute Care Settings; A Literature Review
Publish Year: 1398
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJTMGH-7-4_002
تاریخ نمایه سازی: 7 تیر 1402
Abstract:
Introduction: Familial Mediterranean fever (FMF) is an autosomal recessive disease considered to be the most common entity of a rare group of disorders known as auto-inflammatory syndromes which have acute presentations in emergency settings. Methods: A search of Web of Science, Google Scholar, Cochrane, and PubMed databases for articles published before January ۲۰۱۹ was performed using relevant keywords. Full-text English articles, including review articles, case series, and experimental studies, were evaluated. Unrelated studies were excluded. Based on the selected keywords, ۴۴۰ studies were selected for review. Ultimately, ۶۰ met the study criteria for final assessment. Results: Given the various symptoms and the multiplicity of differential diagnoses, physicians may easily miss diagnosing FMF. Accordingly, emergency medical staff must be trained in order to significantly reduce the number of medical errors and economic costs and to improve the quality of life of involved patients. Conclusion: Although FMF is already known to be an inflammatory entity, more study and investigation of it is required. There is an educational gap in both medical and general populations that should be filled by using new genetic testing and providing appropriate social and medical education.
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Authors
Soleyman Heydari
Department of Surgery, Baqiyatallah University of Medical Sciences, Tehran, Iran
Hosein Namdar
Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Mohammad Javad Behzadnia
Trauma Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
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