Evaluation of Maternal and Fetal Complications in Pregnant Women with Polycystic Ovary Syndrome (PCOS) with Severe and Mild Phenotype

Background & Objective: An essential issue in obstetrics is the prevalence of maternal and fetal complications in pregnant women with polycystic ovary syndrome (PCOS). The purpose of the present study was to investigate the prevalence of pregnancy complications among various phenotypes of pregnant women with PCOS.Materials & Methods: In the current study, the pregnancy period of ۱۴۳ women with PCOS who were referred to the Babylon teaching hospital in Iraq in ۲۰۲۱ was analyzed based on their medical records. These women were separated into two groups based on their PCOS-related clinical symptoms. People in the first group possessed a severe phenotype, while those in the second group possessed a mild phenotype. SPSS version ۲۳ was utilized for comparing maternal and fetal complications during pregnancy and for data analysis.Results: Regarding maternal and fetal complications, there was a significant difference between the two groups regarding low birth weight (LBW) (P<۰.۰۵). In this study, there was no statistically significant difference between PCOS phenotypes and the incidence of gestational diabetes, preterm birth, or spontaneous abortion (P>۰.۰۵). In conclusion, women with a more severe phenotype are more likely to give birth to babies with low birth weight (LBW) (approximately ۱.۹ times).Conclusion: In clinical considerations of pregnant women with PCOS, it appears necessary to consider the disease's phenotype as one of the factors influencing fetal outcomes.

Keywords:

Pregnant women , Polycystic Ovary Syndrome , Maternal-Fetal , low birth weight