The Connection Between Platelets and the Development of Cancer

Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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JR_PMJ-8-29_006

تاریخ نمایه سازی: 1 مرداد 1402

Abstract:

Platelets are tiny (۲-۴ m), anucleate, hematopoietic cells that are discharged into the circulation by bone marrow megakaryocytes. Platelets were formerly thought to be the main agents of hemostasis and thrombosis. Armand Trousseau established a strong link between thrombosis and cancer in ۱۸۶۵. The hypothesis that platelets play many roles in the development of malignancies and in cancer-associated thrombosis is thus supported by a wealth of clinical and experimental data.The functions of tumor-educated platelets (TEPs) in the development of cancer, from primary tumors to subsequent metastatic breakouts, will be covered in this study

Authors

Golnaz Zamanian

Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Peyman Ghoraishizadeh

Department of Clinical Microscopy, Faculty of Medical Technology, Mahidol University, Bangkok, ۱۰۷۰۰, Thailand.

Sajad Hossein Bazrafshani

E.N.T. Department, Worcester Royal Hospital, Worcester, UK

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