Comparison of Trace Elements of Zinc and Copper Between Children with Giardiasis and Healthy
Publish Year: 1394
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JIML-2-3_006
تاریخ نمایه سازی: 14 مرداد 1402
Abstract:
Background and Aims: Giardia lamblia infection is a common cause of food and water-borne diarrhea in non-sanitary communities. Infections are common in children, particularly in child-care centers, backpackers, travelers, and homosexuals. Zinc is necessary for the immune system functions. Zinc deficiency is associated with acute diarrhea. Copper is essential for the production of red blood cells, hemoglobin formation and absorption of iron, and for the activity of various enzymes. However, the association between trace elements and Giardiasis has rarely been investigated. The aim of this experiment was comparison of trace elements of zinc and copper between children with Giardiasis and healthy.
Materials and Methods: The study was carried out between ۳۰ children with Giardiasis and ۳۰ children of control group. It was undertaken in both children aged ۳ to ۱۰ years without any history of Giardiasis and children with symptomatic Giardiasis. The hematological examination was performed. Serum zinc and copper levels were measured. Finally, the data was analyzed using SPSS version ۱۹ statistical software.
Results:. Zinc levels in the study group was remarkably lower than the control group (۶۸.۹۴ vs. ۱۵۳.۹۹ µg/dl, p=۰.۰۰۱). In addition, there was a significant difference in serum copper levels between case (۳۰۹.۲۷ µg/dl) and control (۲۵۳.۱۹ µg/dl) groups (p=۰.۰۰۳).
Conclusions: Giardiasis elevated the serum copper levels, while it decreased the serum zinc.
Keywords:
Authors
Ali Fattahi Bafghi
Medical Parasitology & Mycology Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Mahboubehsadat Sadeghian
Yazd Blood Transfusion Organization, Yazd, Iran.
Akbar Baghiani
Yazd Blood Transfusion Organization, Yazd, Iran.
Arefeh Dehghani Tafti
Biostatics and Epidemiology Department, Faculty of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
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