Investigating the effect of Aloe vera juice on infected wounds in male Wistar rats

Mankind has always sought to find a substance that can accelerate the healing of wounds, and to achieve this goal, he has tested various plant and chemical substances. Due to various reasons such as side effects and the high cost of producing chemical compounds, the attention of researchers has been drawn to plant materials. In this project, the effect of aloe vera-barbarbadensis Miller juice on infected wounds of Wistar rats with Staphylococcus aureus and Pseudomonas aeruginosa strains has been investigated. ۵۰ mice were adapted for one week and divided into five groups of ten. Then, under the same conditions, a wound with an area of ۱.۶۹ cm۲ was created on the back of each neck. The standard bacteria strains of Staphylococcus aureus and Pseudomonas aeruginosa were inoculated on the wound of the group in question and became infected. Aloe vera sap was collected and made into a ۳% ointment with Eucerin base ingredient. After the second day, the treatment of wounds with topical ointment was started and this process was repeated every day and the dimensions of the wounds were recorded. Staphylococcus aureus and Pseudomonas aeruginosa with aloe vera juice treatment progressed in parallel with tetracycline treatment, and the difference between the two was in the healing time of the wound; So that the wounds caused by Staphylococcus aureus and treated with tetracycline improved on the eighth day, and the wounds caused by Pseudomonas aeruginosa were completely closed on the ninth day. However, the wound was treated with aloe vera juice without infection and caused the wounds to close completely on the seventh day. According to the mentioned observations, we conclude that aloe vera juice, in addition to its antibacterial properties, can also show positive effects in wound healing.

Keywords:

skin , aloe vera , Pseudomonas aeruginosa , Staphylococcus aureus , infectious wound