Prevalence of Metabolic Risk Factors Affecting Childhood Nephrolithiasis: A Report from a University Hospital in West of Iran
Publish place: International Journal of Pediatrics، Vol: 8، Issue: 8
Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
View: 103
This Paper With 9 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_INJPM-8-8_004
تاریخ نمایه سازی: 5 شهریور 1402
Abstract:
Background The prevalence of urolithiasis in both infants and children is increasing. The metabolic features contributing to urolithiasis formation in children may vary from those in adult patients. The purpose of this study is to determine the prevalence of urinary metabolic abnormalities and related factors in infants and children with urolithiasis in Kermanshah, West of Iran. Materials and Methods: In this cross-sectional study, ۱۰۴ children and infants with urolithiasis who were admitted to the Pediatrics Nephrology Clinic of Imam Reza Hospital in Kermanshah, Iran in ۲۰۱۸ were investigated. Urinary metabolic abnormalities, including hypercalciuria, hyperuricosuria, hyperoxaluria, and hypocitraturia and cystinuria, were examined using random urine samples. Results: Of the ۱۰۴ children (۶۶ boys and ۳۸ girls) examined, ۶۴ (۶۱.۵%) had at least one urinary metabolic abnormality. Hypercalciuria was the most common (۳۱ patients, ۲۹.۸%), followed by hyperuricosuria (۲۷ patients, ۲۶%), hyperoxaluria (۲۰ patients, ۱۹.۲%), hypocitraturia (۱۳ patients, ۱۲.۵%), and cystinuria (one patient, ۰.۹۶%). Hyperuricosuria (۸۸.۹%) and hypocitraturia (۴۶.۲%) were more common in infants younger than ۱۲ months old compared to those older. No statistically significant association was observed between the frequency of urinary metabolic abnormalities with gender and family history of urolithiasis, but a significant relationship was found between age and prevalence of urinary metabolic abnormalities. Conclusion Hypercalciuria was the most common metabolic abnormality in the urine. Although detection of urinary metabolic abnormalities is important, the role of other variables, like nutritional and climatic factors in the development of childhood nephrolithiasis should be considered too, since no metabolic disorder have been found in more than a third of patients.
Keywords:
Authors
Mohamad Reza Tohidi
Department of Pediatrics, Pediatric Nephrology Division, Kermanshah University of Medical Sciences, Kermanshah, Iran
Abolhassan Seyedzadeh
Department of Pediatrics, Pediatric Nephrology Division, Kermanshah University of Medical Sciences, Kermanshah, Iran
Mohammad Saleh Seyedzadeh
Department of Pediatrics, Pediatric Nephrology Division, Kermanshah University of Medical Sciences, Kermanshah, Iran
Raana Ahmadian
Department of Pediatrics, Pediatric Nephrology Division, Kermanshah University of Medical Sciences, Kermanshah, Iran
Sara Hookari
Department of Pediatrics, Pediatric Nephrology Division, Kermanshah University of Medical Sciences, Kermanshah, Iran