Sirenomelia: A Case Series
Publish place: The Iranian Journal of Neonatology، Vol: 14، Issue: 3
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IRJN-14-3_009
تاریخ نمایه سازی: 12 شهریور 1402
Abstract:
Background: Sirenomelia is a rare congenital anomaly characterized by the fusion of two lower limbs, resulting in the mermaid’s tail appearance. Sirenomelia is a very rare syndrome and can be fatal to the infant. This syndrome might be sporadic or have a genetic basis. The etiology of sirenomelia is unknown but said to be multifactorial. Some maternal factors associated with sirenomelia include diabetes melitus, maternal age under ۲۰ years and monozygote twinning. Case report: This report presented four cases of sirenomelia that occurred during ۲۰۰۶-۲۰۱۹ at Fatemieh Hospital, a tertiary maternal-neonatal center, Hamadan, Iran. All of the pregnancies were complicated by oligohydramnios. None of the mothers were younger than ۲۰ years, and none had diabetes mellitus. Moreover, their drug history during pregnancy was negative. All newborns had low Apgar scores and died a few minutes after birth, indicating their poor outcomes. None of the cases were diagnosed prenatally, and all newborns were firstborn infants. Conclusion: Sirenimelia is a rare lethal condition, which requires prenatal diagnosis for abortion planning.
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Authors
Behnaz Basiri
Pediatric Department, Hamadan University of Medical Sciences, Hamadan, Iran
Maryam Shokouhi
Pediatric Department, Hamadan University of Medical Sciences, Hamadan, Iran
Ramin Mansouri
School of Medicine, Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran
Sara Alipour
School of Medicine, Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran
Yekta Jahedi Tork
School of Medicine, Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran
Kiana Kimiaei Asadi
School of Medicine, Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran
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